OnabotulinumtoxinA injection is given as a number of tiny injections intended to affect only the specific area where injected. However, it is possible that the medication may spread from the area of injection and affect muscles in other areas of the body. If the muscles that control breathing and swallowing are affected, you may develop severe problems breathing or swallowing that may last for several months and may cause death. If you have difficulty swallowing, you may need to be fed through a feeding tube to avoid getting food or drink into your lungs.
Baclofen: Excessive neuromuscular weakness may be exacerbated by coadministration of a botulinum toxin with skeletal muscle relaxants. Advise patients to seek medical assistance if they develop any unusual symptoms (including difficulty with swallowing, speaking, or breathing or walking), or if any existing symptom worsens during use of a botulinum toxin.
Botox is a nerve impulse ‘‘blocker.” It attaches to nerve endings and prevents the release of chemical transmitters, which activate muscles. These chemicals carry the ‘‘message” from the brain that tells a muscle to contract. If the message is blocked, the muscle doesn’t spasm. Botox is given by injection directly into the best Botox in Las Vegas affected muscles. This helps control side effects to other regions of the body. However, nerve endings usually grow new connections to muscles that have not yet been exposed to Botox. So, treatment may be repeated as often as every three months. Botox usually takes full effect within two to four weeks after injection.
The cost of Botox treatments for hyperhidrosis will vary depending upon the size of the body area you need treated and whether insurance will cover any of the price for you. A general estimate of the cost for two underarms is about $1,000. Botulinum toxin injections do not cure hyperhidrosis; your symptoms will go away gradually (usually in about a week) and return gradually. Follow-up injections are required to maintain dryness. These repeat injections may be necessary at intervals varying from 7 to 16 months.
Initiation of stretching programs by therapists along with encouraging good alignment and positioning for functional activities are usually the first interventions done to address the problem of muscle spasticity. If range of motion continues to be a problem, further evaluation by a physician who has experience with muscle spasticity could be helpful.
Botox comes as a crystalline substance from the manufacturer, which then has to be reconstituted with saline or another liquid. Practitioners add varying amounts of liquid when reconstituting it. Although there is no right or wrong amount of liquid to add, most physicians add about 2 mL-3 mL (about a half a teaspoon) of liquid to each vial. Some add quite a bit more, which can lead patients to think they are getting more Botox when, in reality, they are getting the same or less amount of Botox than samples reconstituted in a stronger way. It is the total dose of medication, not the volume of liquid, that leads to the desired effect.